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Nature Cell Biology 5, 952 - 954 (2003)
doi:10.1038/ncb1103-952

Stem cell fusion in the brain

Yevgenia Kozorovitskiy1 & Elizabeth Gould1

  1. Yevgenia Kozorovitskiy & Elizabeth Gould are in the Department of Psychology, Princeton University, Princeton NJ 08544, USA e-mail: goulde@princeton.edu

Bone-marrow-derived stem cells have been shown to contribute to Purkinje neurons in the cerebellum of adult humans and mice. A new study identifies cell fusion as the mechanism underlying this phenomenon, and shows that the bone marrow cell portion of the resulting binucleate heterokaryons acquires the morphological and molecular characteristics of Purkinje neurons over time.

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Nature Letters to Editor (30 Oct 2003)

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