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Nature Cell Biology 5, 851–853 (1 October 2003) | doi:10.1038/ncb1003-851

How attraction turns to repulsion

David G. Wilkinson

To form and stabilize precise patterns of tissue organisation during development, it is essential that cell movement is strictly controlled. For example, some tissues are assembled by the targeted migration of cells, wiring of the nervous system requires the guidance of neuronal growth cones to the correct destination, and tissue patterns are maintained by constraints to the intermingling of adjacent cell populations.