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Letter
Nature Cell Biology 5, 921–927 (1 October 2003) | doi:10.1038/ncb1051
The Salvador partner Hippo promotes apoptosis and cell-cycle exit in Drosophila
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Abstract
Tissue growth during animal development is tightly controlled so that the organism can develop harmoniously. The salvador (sav) gene, which encodes a scaffold protein, has been shown to restrict cell number by coordinating cell-cycle exit and apoptosis during Drosophila development.
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