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Letter
Nature Cell Biology 5, 928–935 (1 October 2003) | doi:10.1038/ncb1046
S-phase checkpoint controls mitosis via an APC-independent Cdc20p function
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Abstract
Cells divide with remarkable fidelity, allowing complex organisms to develop and possess longevity. Checkpoint controls contribute by ensuring that genome duplication and segregation occur without error so that genomic instability, associated with developmental abnormalities and a hallmark of most human cancers, is avoided.
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