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Nature Cell Biology 5, 853–855 (1 October 2003) | doi:10.1038/ncb1003-853

Hippo and its mission for growth control

Hyung Don Ryoo & Hermann Steller

Many animal species exhibit similar body patterns, but have markedly different body sizes. For example, rats are much larger than mice, and house flies dwarf the fruit fly Drosophila melanogaster.