The name game - pp1 - 2

doi:10.1038/ncb0103-1

Full Text - The name game | PDF (59 KB) - The name game

Cell biology in the Antarctic: studying life in the freezer - pp3 - 6

Karin Römisch & Tom Matheson

doi:10.1038/ncb0103-3

Abstract - | Full Text - Cell biology in the Antarctic: studying life in the freezer | PDF (481 KB) - Cell biology in the Antarctic: studying life in the freezer

New insights into an enigmatic tumour suppressor - pp7 - 8

Peter J. Ratcliffe

doi:10.1038/ncb0103-7

Dynamic regulation of the microtubule apparatus is central to cell division, cell migration, polarity and transport. New data demonstrating functional association of the von Hippel-Lindau (VHL) tumour suppressor with microtubules provide a new lead in unravelling VHL tumour suppressor mechanisms.

Full Text - New insights into an enigmatic tumour suppressor | PDF (80 KB) - New insights into an enigmatic tumour suppressor

Defying death: showing Bcl-2 the way home - pp9 - 11

Colin Adrain, Emma M. Creagh & Seamus J. Martin

doi:10.1038/ncb0103-9a

Bcl-2 and Bcl-x_L perform important functions in cell life or death decisions by setting the threshold for activation of the programmed cell death machinery. FKBP38, a member of the immunophilin family, has now been identified as a new Bcl-2/Bcl-x_L-binding partner. Furthermore, FKBP38 seems to be crucial in targeting Bcl-2/Bcl-x_L to the correct cellular locations.

Full Text - Defying death: showing Bcl-2 the way home | PDF (404 KB) - Defying death: showing Bcl-2 the way home

The Hitchhiker's Guide to HIV - p9

Alison Schuldt

doi:10.1038/ncb0103-9b

Full Text - The Hitchhiker's Guide to HIV | PDF (358 KB) - The Hitchhiker's Guide to HIV

A genetic hierarchy controlling cell polarity - pp12 - 14

Kevin Johnson & Andreas Wodarz

doi:10.1038/ncb0103-12

The establishment and maintenance of apicobasal cell polarity is of fundamental importance for most physiological functions of epithelial tissues. In Drosophila melanogaster, several critical regulators of cell polarity have been identified over the past years, but we are just beginning to understand how these genes interact with each other. Two new papers now shed light on the genetic hierarchy that rules this process.

Full Text - A genetic hierarchy controlling cell polarity | PDF (423 KB) - A genetic hierarchy controlling cell polarity

ZAP-ping T-cell activation - p13

Sarah Greaves

doi:10.1038/ncb0103-13

Full Text - ZAP-ping T-cell activation | PDF (180 KB) - ZAP-ping T-cell activation

Cell of the month: Plant vessel elements trans-differentiated from mesophyll cells in vitro - p15

doi:10.1038/ncb0103-15

Full Text - Cell of the month: Plant vessel elements trans-differentiated from mesophyll cells in vitro | PDF (504 KB) - Cell of the month: Plant vessel elements trans-differentiated from mesophyll cells in vitro

Eukaryotic cells and microbial pathogens: a familiar couple take centre stage - pp16 - 19

Craig R. Roy & F. Gisou van der Goot

doi:10.1038/ncb0103-16

Abstract - | Full Text - Eukaryotic cells and microbial pathogens: a familiar couple take centre stage | PDF (96 KB) - Eukaryotic cells and microbial pathogens: a familiar couple take centre stage

How my garden does grow - p20

Timothy Nelson reviews Molecular Plant Biology: A Practical Approach – Volumes 1 and 2 by Philip M. Gilmartin & Chris Bowler

doi:10.1038/ncb0103-20

Full Text - How my garden does grow | PDF (215 KB) - How my garden does grow

Unconventional tethering of Ulp1 to the transport channel of the nuclear pore complex by karyopherins - pp21 - 27

Vikram Govind Panse, Bernhard Küster, Thomas Gerstberger & Ed Hurt

doi:10.1038/ncb893

Abstract - | Full Text - Unconventional tethering of Ulp1 to the transport channel of the nuclear pore complex by karyopherins | PDF (4,288 KB) - Unconventional tethering of Ulp1 to the transport channel of the nuclear pore complex by karyopherins | Supplementary information

Inherent calcineurin inhibitor FKBP38 targets Bcl-2 to mitochondria and inhibits apoptosis - pp28 - 37

Michiko Shirane & Keiichi I. Nakayama

doi:10.1038/ncb894

Abstract - | Full Text - Inherent calcineurin inhibitor FKBP38 targets Bcl-2 to mitochondria and inhibits apoptosis | PDF (4,824 KB) - Inherent calcineurin inhibitor FKBP38 targets Bcl-2 to mitochondria and inhibits apoptosis | Supplementary information

Signalling and crosstalk of Rho GTPases in mediating axon guidance - pp38 - 45

Xiao-bing Yuan, Ming Jin, Xiaohua Xu, Yuan-quan Song, Chien-ping Wu, Mu-ming Poo & Shumin Duan

doi:10.1038/ncb895

Abstract - | Full Text - Signalling and crosstalk of Rho GTPases in mediating axon guidance | PDF (1,451 KB) - Signalling and crosstalk of Rho GTPases in mediating axon guidance

Interactions between the crumbs, lethal giant larvae and bazooka pathways in epithelial polarization - pp46 - 52

Guy Tanentzapf & Ulrich Tepass

doi:10.1038/ncb896

First Paragraph - | Full Text - Interactions between the crumbs, lethal giant larvae and bazooka pathways in epithelial polarization | PDF (2,145 KB) - Interactions between the crumbs, lethal giant larvae and bazooka pathways in epithelial polarization

Integrated activity of PDZ protein complexes regulates epithelial polarity - pp53 - 58

David Bilder, Markus Schober & Norbert Perrimon

doi:10.1038/ncb897

First Paragraph - | Full Text - Integrated activity of PDZ protein complexes regulates epithelial polarity | PDF (2,660 KB) - Integrated activity of PDZ protein complexes regulates epithelial polarity | Supplementary information

Vimentin is secreted by activated macrophages - pp59 - 63

Nirit Mor-Vaknin, Antonello Punturieri, Kajal Sitwala & David M. Markovitz

doi:10.1038/ncb898

First Paragraph - | Full Text - Vimentin is secreted by activated macrophages | PDF (1,243 KB) - Vimentin is secreted by activated macrophages | Supplementary information

Regulation of microtubule stability by the von Hippel-Lindau tumour suppressor protein pVHL - pp64 - 70

Alexander Hergovich, Joanna Lisztwan, Robert Barry, Pia Ballschmieter & Wilhelm Krek

doi:10.1038/ncb899

First Paragraph - | Full Text - Regulation of microtubule stability by the von Hippel-Lindau tumour suppressor protein pVHL | PDF (5,050 KB) - Regulation of microtubule stability by the von Hippel-Lindau tumour suppressor protein pVHL | Supplementary information

-Tubulin is required for centriole duplication and microtubule organization - pp71 - 76

Paul Chang, Thomas H. Giddings, Jr, Mark Winey & Tim Stearns

doi:10.1038/ncb900

First Paragraph - | Full Text - -Tubulin is required for centriole duplication and microtubule organization | PDF (2,215 KB) - -Tubulin is required for centriole duplication and microtubule organization

Yeast epsin-related proteins required for Golgi–endosome traffic define a -adaptin ear-binding motif - pp77 - 81

Mara C. Duncan, Giancarlo Costaguta & Gregory S. Payne

doi:10.1038/ncb901

First Paragraph - | Full Text - Yeast epsin-related proteins required for Golgi–endosome traffic define a -adaptin ear-binding motif | PDF (283 KB) - Yeast epsin-related proteins required for Golgi–endosome traffic define a -adaptin ear-binding motif

The Drosophila HOAP protein is required for telomere capping - pp82 - 84

Giovanni Cenci, Giorgia Siriaco, Grazia D. Raffa, Rebecca Kellum & Maurizio Gatti

doi:10.1038/ncb902

Abstract - | Full Text - The Drosophila HOAP protein is required for telomere capping | PDF (1,581 KB) - The Drosophila HOAP protein is required for telomere capping

Erratum: Bicaudal-D regulates COPI-independent Golgi–ER transport by recruiting the dynein–dynactin motor complex - p84

doi:10.1038/ncb903

Full Text - Erratum: Bicaudal-D regulates COPI-independent Golgi–ER transport by recruiting the dynein–dynactin motor complex | PDF (1,876 KB) - Erratum: Bicaudal-D regulates COPI-independent Golgi–ER transport by recruiting the dynein–dynactin motor complex

Corrigendum: 53BP1 functions in an ATM-dependent checkpoint pathway that is constitutively activated in human cancer - p84

doi:10.1038/ncb904

Full Text - Corrigendum: 53BP1 functions in an ATM-dependent checkpoint pathway that is constitutively activated in human cancer | PDF (34 KB) - Corrigendum: 53BP1 functions in an ATM-dependent checkpoint pathway that is constitutively activated in human cancer