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Brief Communication
Nature Cell Biology 4, 616–620 (1 August 2002) | doi:10.1038/ncb830
Myosin VI is required for E-cadherin-mediated border cell migration
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Abstract
Myosin VI (MyoVI) is a pointed-end-directed, actin-based motor protein, and mutations in the gene result in disorganization of hair cell stereocilia and cause deafness in mice. MyoVI also localizes to the leading edges of growth-factor-stimulated fibroblast cells and has been suggested to be involved in cell motility.
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