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Review

Nature Cell Biology 4, E203–E206 (1 August 2002) | doi:10.1038/ncb0802-e203

Kinase- and phosphatase-anchoring proteins: harnessing the dynamic duo

Andrea L. Bauman & John D. Scott

Protein–protein interactions contribute to the spatial and temporal resolution of many signal transduction cascades. Here, we discuss recent advances in our understanding of phosphatase-targeting subunits, kinase-anchoring proteins and the multiprotein signalling networks that they assemble.