Table of contents
July 2002, Volume 4 No 7 ppE163-546
About the coverLetters to Editor
No endogenous A
production in presenilin-deficient fibroblasts - pE164
Omar Nyabi, Stefan Pype, Marc Mercken, An Herreman, Paul Saftig, Katleen Craessaerts, Lutgarde Serneels, Wim Annaert & Bart De Strooper
doi:10.1038/ncb0702-e164a
Full Text - No endogenous A
production in presenilin-deficient fibroblasts | PDF (157 KB) - No endogenous A
production in presenilin-deficient fibroblasts
Potential external source of A
in biological samples - ppE164 - E165
Marcus O.W. Grimm, Inge Tomic & Tobias Hartmann
doi:10.1038/ncb0702-e164b
Full Text - Potential external source of A
in biological samples | PDF (157 KB) - Potential external source of A
in biological samples
Reply: Potential external source of A
in biological samples - ppE165 - E166
Agnes Petit, Bruno Vincent, Sabine Scarzello, Marianna Armogida, Cristine Alves da Costa & Frédéric Checler
doi:10.1038/ncb0702-e165
Full Text - Reply: Potential external source of A
in biological samples | PDF (157 KB) - Reply: Potential external source of A
in biological samples
News and Views
Cadmium blocks viral invasion in plants - ppE167 - E168
John P. Carr & Alex M. Murphy
doi:10.1038/ncb0702-e167
To move between different parts of their hosts, most plant viruses exploit the phloem. Plants exposed to subtoxic levels of cadmium ions can resist this viral highjacking of their transportation network. New work in this issue of Nature Cell Biology has identified a novel, chemically induced, glycine-rich protein that is responsible for inhibiting the long-distance movement of turnip vein clearing tobamovirus (TVCV) in tobacco plants.
Full Text - Cadmium blocks viral invasion in plants | PDF (257 KB) - Cadmium blocks viral invasion in plants
See also: Article by Ueki & Citovsky
May the force be with you: Myosin-X in phagocytosis - ppE169 - E171
Philippe Chavrier
doi:10.1038/ncb0702-e169
Engulfment of pathogens by phagocytosis requires the coordination of actin assembly and progressive 'zippering' of pseudopodial membranes around the particle. Recent work shows that Myosin-X, which binds phosphatidylinositol-3-OH kinase (PI(3)K) products through its pleckstrin homology (PH) domains, is required for phagocytosis, thereby providing a molecular basis for the function of PI(3)K in pseudopod extension.
Full Text - May the force be with you: Myosin-X in phagocytosis | PDF (166 KB) - May the force be with you: Myosin-X in phagocytosis
See also: Article by Cox et al.
Leading the way - pE171
Ruedi Meili & Richard A. Firtel
doi:10.1038/ncb0702-e171
Full Text - Leading the way | PDF (123 KB) - Leading the way
See also: Brief Communication by Weiner et al. | Brief Communication by Wang et al.
Crème de la Kremen of Wnt signalling inhibition - pE172
Ute Rothbächer & Patrick Lemaire
doi:10.1038/ncb0702-e172
Full Text - Crème de la Kremen of Wnt signalling inhibition | PDF (173 KB) - Crème de la Kremen of Wnt signalling inhibition
Book Reviews
Benefits and hazards of protein destruction - pE174
Peter Kloetzel reviews Protein Degradation in Health and Disease by M. Reboud-Ravaux
doi:10.1038/ncb0702-e174
Full Text - Benefits and hazards of protein destruction | PDF (94 KB) - Benefits and hazards of protein destruction
Embryonic stem cell cookery - pE175
Janet Rossant reviews Embryonic stem cells: Methods and Protocols by Kursad Turksen
doi:10.1038/ncb0702-e175
Full Text - Embryonic stem cell cookery | PDF (183 KB) - Embryonic stem cell cookery
Review
The Ran GTPase as a marker of chromosome position in spindle formation and nuclear envelope assembly - ppE177 - E184
Martin Hetzer, Oliver J. Gruss & Iain W. Mattaj
doi:10.1038/ncb0702-e177
Abstract - The Ran GTPase as a marker of chromosome position in spindle formation and nuclear envelope assembly | Full Text - The Ran GTPase as a marker of chromosome position in spindle formation and nuclear envelope assembly | PDF (637 KB) - The Ran GTPase as a marker of chromosome position in spindle formation and nuclear envelope assembly
Articles
Myosin X is a downstream effector of PI(3)K during phagocytosis - pp469 - 477
Dianne Cox, Jonathan S. Berg, Michael Cammer, John O. Chinegwundoh, Benjamin M. Dale, Richard E. Cheney & Steven Greenberg
doi:10.1038/ncb805
Abstract - Myosin X is a downstream effector of PI(3)K during phagocytosis | Full Text - Myosin X is a downstream effector of PI(3)K during phagocytosis | PDF (1,370 KB) - Myosin X is a downstream effector of PI(3)K during phagocytosis | Supplementary information
See also: News and Views by Chavrier
The systemic movement of a tobamovirus is inhibited by a cadmium-ion-induced glycine-rich protein - pp478 - 486
Shoko Ueki & Vitaly Citovsky
doi:10.1038/ncb806
Abstract - The systemic movement of a tobamovirus is inhibited by a cadmium-ion-induced glycine-rich protein | Full Text - The systemic movement of a tobamovirus is inhibited by a cadmium-ion-induced glycine-rich protein | PDF (1,999 KB) - The systemic movement of a tobamovirus is inhibited by a cadmium-ion-induced glycine-rich protein
See also: News and Views by Carr & Murphy
Metastasis is driven by sequential elevation of H-ras and Smad2 levels - pp487 - 494
Martin Oft, Rosemary J. Akhurst & Allan Balmain
doi:10.1038/ncb807
Abstract - Metastasis is driven by sequential elevation of H-ras and Smad2 levels | Full Text - Metastasis is driven by sequential elevation of H-ras and Smad2 levels | PDF (1,478 KB) - Metastasis is driven by sequential elevation of H-ras and Smad2 levels
Filamin A-interacting protein (FILIP) regulates cortical cell migration out of the ventricular zone - pp495 - 501
Takashi Nagano, Takunari Yoneda, Yumiko Hatanaka, Chikara Kubota, Fujio Murakami & Makoto Sato
doi:10.1038/ncb808
Abstract - Filamin A-interacting protein (FILIP) regulates cortical cell migration out of the ventricular zone | Full Text - Filamin A-interacting protein (FILIP) regulates cortical cell migration out of the ventricular zone | PDF (6,280 KB) - Filamin A-interacting protein (FILIP) regulates cortical cell migration out of the ventricular zone
Cajal Body dynamics and association with chromatin are ATP-dependent - pp502 - 508
Melpomeni Platani, Ilya Goldberg, Angus I. Lamond & Jason R. Swedlow
doi:10.1038/ncb809
Abstract - Cajal Body dynamics and association with chromatin are ATP-dependent | Full Text - Cajal Body dynamics and association with chromatin are ATP-dependent | PDF (2,590 KB) - Cajal Body dynamics and association with chromatin are ATP-dependent | Supplementary information
Brief Communications
Lipid products of PI(3)Ks maintain persistent cell polarity and directed motility in neutrophils - pp513 - 518
Fei Wang, Paul Herzmark, Orion D. Weiner, Supriya Srinivasan, Guy Servant & Henry R. Bourne
doi:10.1038/ncb810
Abstract - Lipid products of PI(3)Ks maintain persistent cell polarity and directed motility in neutrophils | Full Text - Lipid products of PI(3)Ks maintain persistent cell polarity and directed motility in neutrophils | PDF (857 KB) - Lipid products of PI(3)Ks maintain persistent cell polarity and directed motility in neutrophils | Supplementary information
See also: News and Views by Meili & Firtel
A PtdInsP3- and Rho GTPase-mediated positive feedback loop regulates neutrophil polarity - pp509 - 513
Orion D. Weiner, Paul O. Neilsen, Glenn D. Prestwich, Marc W. Kirschner, Lewis C. Cantley & Henry R. Bourne
doi:10.1038/ncb811
Abstract - A PtdInsP: 3: - and Rho GTPase-mediated positive feedback loop regulates neutrophil polarity | Full Text - A PtdInsP3- and Rho GTPase-mediated positive feedback loop regulates neutrophil polarity | PDF (380 KB) - A PtdInsP3- and Rho GTPase-mediated positive feedback loop regulates neutrophil polarity | Supplementary information
See also: News and Views by Meili & Firtel
Nuclear exclusion of Smad2 is a mechanism leading to loss of competence - pp519 - 522
Oliver H. Grimm & J. B. Gurdon
doi:10.1038/ncb812
Abstract - Nuclear exclusion of Smad2 is a mechanism leading to loss of competence | Full Text - Nuclear exclusion of Smad2 is a mechanism leading to loss of competence | PDF (228 KB) - Nuclear exclusion of Smad2 is a mechanism leading to loss of competence
Distinct roles for cyclins E and A during DNA replication complex assembly and activation - pp523 - 528
Dawn Coverley, Heike Laman & Ronald A. Laskey
doi:10.1038/ncb813
Abstract - Distinct roles for cyclins E and A during DNA replication complex assembly and activation | Full Text - Distinct roles for cyclins E and A during DNA replication complex assembly and activation | PDF (706 KB) - Distinct roles for cyclins E and A during DNA replication complex assembly and activation
Nucleophosmin regulates the stability and transcriptional activity of p53 - pp529 - 533
Emanuela Colombo, Jean-Christophe Marine, Davide Danovi, Brunangelo Falini & Pier Giuseppe Pelicci
doi:10.1038/ncb814
Abstract - Nucleophosmin regulates the stability and transcriptional activity of p53 | Full Text - Nucleophosmin regulates the stability and transcriptional activity of p53 | PDF (1,884 KB) - Nucleophosmin regulates the stability and transcriptional activity of p53
The Vps27p–Hse1p complex binds ubiquitin and mediates endosomal protein sorting - pp534 - 539
Patricia S. Bilodeau, Jennifer L. Urbanowski, Stanley C. Winistorfer & Robert C. Piper
doi:10.1038/ncb815
Abstract - The Vps27p-Hse1p complex binds ubiquitin and mediates endosomal protein sorting | Full Text - The Vps27p–Hse1p complex binds ubiquitin and mediates endosomal protein sorting | PDF (848 KB) - The Vps27p–Hse1p complex binds ubiquitin and mediates endosomal protein sorting | Supplementary information
The role of NFAT transcription factors in integrin-mediated carcinoma invasion - pp540 - 544
Sebastien Jauliac, Cristina López-Rodriguez, Leslie M. Shaw, Lawrence F. Brown, Anjana Rao & Alex Toker
doi:10.1038/ncb816
Abstract - The role of NFAT transcription factors in integrin-mediated carcinoma invasion | Full Text - The role of NFAT transcription factors in integrin-mediated carcinoma invasion | PDF (1,157 KB) - The role of NFAT transcription factors in integrin-mediated carcinoma invasion | Supplementary information
Errata
Erratum: Regulation of Drosophila IAP1 degradation and apoptosis by reaper and ubcD1 - p546
doi:10.1038/ncb818
Full Text - Erratum: Regulation of Drosophila IAP1 degradation and apoptosis by reaper and ubcD1 | PDF (55 KB) - Erratum: Regulation of Drosophila IAP1 degradation and apoptosis by reaper and ubcD1
Erratum: A novel PKC-regulated mechanism controls CD44-ezrin association and directional cell motility - p546
doi:10.1038/ncb819
Full Text - Erratum: A novel PKC-regulated mechanism controls CD44-ezrin association and directional cell motility | PDF (51 KB) - Erratum: A novel PKC-regulated mechanism controls CD44-ezrin association and directional cell motility
Erratum: Cover caption - June 2002 issue - p546
doi:10.1038/ncb820
Full Text - Erratum: Cover caption - June 2002 issue | PDF (43 KB) - Erratum: Cover caption - June 2002 issue


