News and Views


Nature Cell Biology 4, E75 - E76 (2002)
doi:10.1038/ncb0402-e75

Integrin regulation of growth factor receptors

Kenneth M. Yamada1 & Sharona Even-Ram1

  1. Kenneth M. Yamada and Sharona Even-Ram are in the Craniofacial Developmental Biology and Regeneration Branch, National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, MD 20892, USA
    e-mail: kyamada@dir.nidcr.nih.gov
    e-mail: sram@dir.nidcr.nih.gov


Integrins are receptors for extracellular matrix proteins that engage in reciprocal crosstalk with growth factor receptors. Recent work identifies a unique mechanism for the regulation of growth factor receptor phosphorylation by integrins, indicating multiple ways of achieving cooperation between these major signalling systems.

Top


MORE ARTICLES LIKE THIS
These links to content published by NPG are automatically generated

REFERENCE
Integrins: Signalling and Disease
Nature Encyclopaedia of Life Sciences

REVIEWS
Paxillin and focal adhesion signalling
Nature Cell Biology Review Article (01 Dec 2000)
 See all 2 matches for Reviews

NEWS AND VIEWS
Casting light on focal adhesions
Nature Genetics News and Views (01 Aug 1998)

RESEARCH
Activation of the focal adhesion kinase signaling pathway by structural alterations in the carboxyl-terminal region of c-Crk II
Oncogene Original Article (22 Feb 2001)
A scaffold protein in the c-Jun N-terminal kinase signaling pathway is associated with focal adhesion kinase and tyrosine-phosphorylated
Oncogene Original Article (19 Sep 2002)
 See all 10 matches for Research


Extra navigation

Subscribe to Nature Cell Biology

Subscribe

Open Innovation Challenges

naturejobs