Supplementary information

From the following article

53BP1 functions in an ATM-dependent checkpoint pathway that is constitutively activated in human cancer

Richard A. DiTullio, Jr, Tamara A. Mochan, Monica Venere, Jirina Bartkova, Maxwell Sehested, Jiri Bartek & Thanos D. Halazonetis

Nature Cell Biology 4, 998 - 1002 (2002) Published online: 25 November 2002

doi:10.1038/ncb892

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Supplementary Figures

Figure S1
Suppression of 53BP1 protein levels by siRNA does not affect the cell cycle profile of non-irradiated cells.

Figure S2
Suppression of 53BP1 protein levels by siRNA does not affect the gamma-H2AX foci present in non-irradiated SAOS2 cells.

Figure S3
Specificity of the immunohistochemistry assay for Chk2 phosphorylation at Thr68.

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