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Brief Communication

Nature Cell Biology 4, 907–912 (1 November 2002) | doi:10.1038/ncb875

Wound healing recapitulates morphogenesis in Drosophila embryos

William Wood , Antonio Jacinto , Richard Grose , Sarah Woolner , Jonathan Gale , Clive Wilson & Paul Martin

The capacity to repair a wound is a fundamental survival mechanism that is activated at any site of damage throughout embryonic and adult life. To study the cell biology and genetics of this process, we have developed a wounding model in Drosophila melanogaster embryos that allows live imaging of rearrangements and changes in cell shape, and of the cytoskeletal machinery that draws closed an in vivo wound.