News and Views

Nature Cell Biology 4, E251 - E253 (2002)
doi:10.1038/ncb1102-e251b

Drosophila, actin and videotape — new insights in wound healing

Stéphane Noselli1

  1. Stéphane Noselli is in the Institut de Recherches 'Signalisation, Biologie du Developpement et Cancer', UMR 6543 – CNRS, Parc Valrose, 06108 NICE cedex 2, France
    e-mail: noselli@unice.fr

The combined use of laser ablation and live imaging in Drosophila melanogaster embryos provides new ways to visualize the dynamics of wound healing. Analysis of lesions made in living embryos mutant for small GTPases reveal distinct and unexpected roles for actin cables and protrusions in wound repair. Hole closure is definitely more complex than simply pulling a string.

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