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Nature Cell Biology 4, E230–E232 (1 October 2002) | doi:10.1038/ncb1002-e230

A glimpse of coated vesicle creation? Well almost|[excl]|

Francesca Santini & James H. Keen

During endocytosis, a variety of cargo molecules and cell-surface receptors (such as the low-density lipoprotein receptor and the transferrin receptor) are concentrated into clathrin-coated regions of the PM. These regions invaginate to form pits and then eventually detach from the surface.