Review abstract
Nature Cell Biology 4, E236 - E242 (2002)
doi:10.1038/ncb1002-e236
Motoring around the Golgi
Victoria J. Allan1, Heather M. Thompson2 & Mark A. McNiven2
Abstract
The Golgi apparatus is a dynamic organelle through which nascent secretory and transmembrane proteins are transported, post-translationally modified and finally packaged into carrier vesicles for transport along the cytoskeleton to a variety of destinations. In the past decade, studies have shown that a number of 'molecular motors' are involved in maintaining the proper structure and function of the Golgi apparatus. Here, we review just some of the many functions performed by these mechanochemical enzymes — dyneins, kinesins, myosins and dynamin — in relation to the Golgi apparatus.
- School of Biological Sciences, University of Manchester, Manchester M13 9PT, UK
- GI Basic Research and Department of Biochemistry and Molecular Biology, Mayo Clinic and Foundation, Rochester, MN 55905, USA. e-mail: mmcniven@mayo.edu
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