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Nature Cell Biology 4, E6 - E8 (2002)
doi:10.1038/ncb0102-e6
Strabismus comes into focus
Jeffrey D. Axelrod1
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Jeffrey D. Axelrod is in the Department of Pathology, Stanford University School of Medicine, 300 Pasteur Drive, Stanford, CA 94305-5324, USA
e-mail: jaxelrod@cmgm.stanford.edu
Abstract
At least one member of the Frizzled (Fz) family of receptors, together with the downstream signalling protein Dishevelled, participates in several distinct, yet closely related signal transduction pathways. Activation of the correct signal transduction pathway is critical. Here, a new study suggests that the transmembrane protein Strabismus participates in this decision.
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