Rüdiger Klein is in the Max-Planck Institute of Neurobiology, Department of Molecular Neurobiology, Am Klopferspitz 18A, D-82152 Martinsried, Germany. rklein@neuro.mpg.de
Integrins are cell surface receptors for extracellular matrix proteins and, as such, regulate adhesive cell−matrix interactions. New findings indicate that the 4 integrin subunit can also function as a signalling effector for the activated receptor tyrosine kinase Met and enhance invasive growth independent of its adhesive role.
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4 integrin subunit can also function as a signalling effector for the activated receptor tyrosine kinase Met and enhance invasive growth independent of its adhesive role.
4 cytoplasmic domain
