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Nature Cell Biology 3, E158 (1 July 2001) | doi:10.1038/35083107
PAR-1 helps Wnt to get rid of JNK
Abstract
Wnt/Wingless (Wg) signalling is critical for normal embryonic development, and deregulation of the Wnt pathway can lead to aberrant development or cancer. The Dishevelled (Dsh) protein is phosphorylated and activated as a result of Wnt-binding to its receptor Frizzled (Fz).
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