Kari Alitalo is in the Molecular/Cancer Biology Laboratory, Biomedicium Helsinki, Haartmaninkatu 8, 00014 University of Helsinki, Finland
kari.alitalo@helsinki.fi
No mutation in the fibroblast-growth-factor receptor-4 (FGFR-4) signalling pathway has so far been associated with either heritable human diseases or cancer. A new study now implicates N-CAM−FGFR-4 signalling in the regulation of tumour-cell−matrix adhesion and in the metastatis of pancreatic -cell tumours.
-cell tumours.
