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Volume 3 Issue 6, June 2001

Electron microscopy images of coated buds and vesicles on liposomes. Cover design: Majo Xeridat [article, p531]

Volume 3 Issue 6

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  • The endosomal system includes distinct endocytic compartments where decisions are made that determine the destinations of extracellular and plasma membrane materials that have been internalized. A new family of proteins has been found that governs the exit of material from one of these endocytic organelles, the endosomal recycling compartment (ERC).

    • Beverly Wendland
    News & Views

  • In the Drosophila egg, during signalling through the epidermal growth factor (EGF) receptor, a conformational switch, which is dependent on mitogen-activated protein kinase (MAPK) leads to the Cf2 transcriptio-nal repressor being targeted for proteolysis. Recent work shows that this switch is catalysed by the Drosophila homologue of Pin1, a peptidyl-prolyl isomerase.

    • Matthew Freeman
    News & Views

  • Time-lapse analyses of normal cellular behaviours and signalling by fibroblast growth factor (FGF) provide new insights into the cell motions and molecules that form the posterior nervous system.

    • Catherine E. Krull
    • Robb Krumlauf
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