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Nature Cell Biology 3, E110–E112 (1 May 2001) | doi:10.1038/35074631
Getting a grip: new insights for cell adhesion and traction
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Abstract
The biophysical interactions of the cell with the extracellular matrix generate forces that are transmitted from the cell to its surroundings and from the matrix to the cell. Outside-in mechanical forces exert a myriad of roles on cell behaviour by activating various biochemical signalling pathways and regulating gene expression.
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