News and Views
Nature Cell Biology 3, E108 - E110 (2001)
doi:10.1038/35074625
Caveolae on the move
Suzanne R. Pfeffer1
-
Suzanne R. Pfeffer is in the Department of Biochemistry,
Stanford University School of Medicine, Stanford, California
94305-5307 USA.
e-mail: pfeffer@cmgm.stanford.edu
Abstract
Caveolae deliver simian virus 40 (SV40) to a new compartment called a caveosome, where the virus is sorted for transport to the smooth endoplasmic reticulum (ER). This pathway bypasses other endocytic organelles, and early steps may be shared by lipid rafts and certain glycosylphosphatidylinositol (GPI)-linked proteins.
