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Nature Cell Biology 3, E105 - E108 (2001)
doi:10.1038/35074618

Centrosomes as command centres for cellular control

Stephen J. Doxsey1

  1. Stephen J. Doxsey is in the Program in Molecular Medicine, University of Massachusetts Medical School, 373 Plantation Street, Worcester, Massachusetts 01605, USA.
    e-mail: stephen.doxsey@umassmed.edu


For almost a century, our understanding of the tiny structure at the centre of the cell called the centrosome was limited to its ability to organize mitotic spindles and other microtubule arrays. However, recent studies have indicated new roles for centrosomes in cytokinesis and cell-cycle progression.

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