Nature Cell Biology
3, E46 - E49 (2001)
doi:10.1038/35055152
S-nitrosylation: spectrum and specificityDouglas T. Hess, Akio Matsumoto, Raphael Nudelman
& Jonathan S. Stamler
Douglas T. Hess, Akio Matsumoto, Raphael Nudelman and Jonathan
S. Stamler in the Howard Hughes Medical Institute and the Departments
of Medicine and Biochemistry, Duke University Medical Center,
Durham, North Carolina 27710, USA.
staml001@mc.duke.edu
Nitric oxide regulates a broad functional spectrum of proteins by
S-nitrosylation. Specificity is conferred by acid−base and hydrophobic
motifs that target critical cysteine residues and by protein−protein
interactions that confine the signals in space.
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