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Nature Cell Biology  3, E46 - E49 (2001)
doi:10.1038/35055152

S-nitrosylation: spectrum and specificity

Douglas T. Hess, Akio Matsumoto, Raphael Nudelman & Jonathan S. Stamler

Douglas T. Hess, Akio Matsumoto, Raphael Nudelman and Jonathan S. Stamler in the Howard Hughes Medical Institute and the Departments of Medicine and Biochemistry, Duke University Medical Center, Durham, North Carolina 27710, USA.
staml001@mc.duke.edu

Nitric oxide regulates a broad functional spectrum of proteins by S-nitrosylation. Specificity is conferred by acid−base and hydrophobic motifs that target critical cysteine residues and by protein−protein interactions that confine the signals in space.

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Nature Cell Biology
ISSN: 1465-7392
EISSN: 1476-4679
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