1. Timothy S. Zheng is at Biogen Inc., 14 Cambridge Center, Cambridge, Massachusetts 02142, USA.
   e-mail: timothy_zheng@biogen.com

Abstract

Members of the Bcl-2 family are critical regulators of apoptosis and have become attractive targets for the development of anti-cancer drugs. The latest discovery of small-molecule inhibitors of Bcl-2 proteins may provide the sought-after leads for the development of new anti-cancer therapy

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