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Nature Cell Biology 3, E245 - E246 (2001)
doi:10.1038/ncb1101-e245
High-speed mass transit for poxviruses on microtubules
Bernard Moss1 & Brian M. Ward1
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Bernard Moss and Brian M. Ward are at the Laboratory of Viral Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, 4 Center Drive, MSC 0445, Bethesda, Maryland 20892-0445, USA.
e-mail: bmoss@niaid.nih.gov
Abstract
Commuters can ride a high-speed mass-transit system from the city centre to the suburbs and then engage a private vehicle for the final leg home. Similarly, vaccinia virions travel to the cell periphery on microtubule tracks, disembark near the plasma membrane, and acquire individual actin tails for propulsion on microvilli towards adjacent cells.
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