Access
To read this article in full you may need to log in, make a payment or gain access through a site license (see right).
News and Views
Nature Cell Biology 3, E229–E231 (1 October 2001) | doi:10.1038/ncb1001-e229
Sugar-coated pathways for developmental patterning
Abstract
Modification of proteins by the covalent attachment of carbohydrate chains has emerged as a key feature of several developmental signal-transduction pathways. Heparan sulphate proteoglycans (HSPGs), proteins bearing long unbranched sugar polymer chains, influence the assembly or activity of signalling complexes at the cell surface and are important for Wingless (Wg/Wnt), Hedgehog (Hh), transforming growth factor-β (TGF-β) and fibroblast growth factor (FGF) signalling.
To read this article in full you may need to log in, make a payment or gain access through a site license (see right).
