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Nature Cell Biology 3, E226 - E228 (2001)
doi:10.1038/ncb1001-e226
Catch and pull a microtubule: getting a grasp on the cortex
- Viki Allan is in the School of Biological Sciences, 2.205 Stopford Building, University of Manchester, Oxford Road, Manchester M13 9PT, UK
- Inke Näthke is in the Division and Cell and Developmental Biology, School of Life Sciences, University of Dundee, Dundee DD1 5EH, UK e-mail: i.s.nathke@dundee.ac.uk
Abstract
Cytoskeletal attachment to the cell cortex is crucial for mechanical and signalling events at the plasma membrane. The adenomatous polyposis coli (APC) protein, as well as
-catenin in a complex with cytoplasmic dynein, is implicated in mediating such cortical attachment.
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