Historical Perspective abstract
Nature Cell Biology 3, E17 - E21 (2001)
doi:10.1038/35050656
Mitosis: a history of division
T. J. Mitchison1 & E. D. Salmon2
Abstract
Mitosis has been studied since the early 1880s, to the extent that we now have a detailed, but still incomplete, description of spindle dynamics and mechanics, a sense of potential mechanochemical and regulatory mechanisms at a molecular level, and a long list of mitotic proteins. Here we present a personal view of how far we have come, and where we need to go to fully understand the mechanisms involved in mitosis.
- Timothy Mitchison is in the Deparment of Cell Biology, Harvard Medical School, Boston, Massachusetts, USA
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Edward. D. Salmon is in the Department of Biology, University of North Carolina, Chapel Hill, North Carolina, USA
e-mail: timothy_mitchison@hms.harvard.edu
