Volume 2 Issue 8, August 2000

Deconvolution image of endogenous mPAR-6 in dissociated murine cortical neurons isolated from 16.5-day-old embryos. Eight hours after dissociation and plating, cortical neurons were fixed and stained with a polyclonal antibody raised against mPAR-6 (red). Neurons were counterstained with Heochst 333298 (blue). Endogenous mPAR-6 is enriched in perinuclear structures and filamentous structures in developing growth cones.

Article

Heat-shock protein 70 inhibits apoptosis by preventing recruitment of procaspase-9 to the Apaf-1 apoptosome

Helen M. Beere
Beni B. Wolf
Douglas R. Green
Article 04 Jul 2000
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Negative regulation of the Apaf-1 apoptosome by Hsp70

Ayman Saleh
Srinivasa M. Srinivasula
Emad S. Alnemri
Article 06 Jul 2000
CENP-E forms a link between attachment of spindle microtubules to kinetochores and the mitotic checkpoint

Xuebiao Yao
Ariane Abrieu
Don W. Cleveland
Article 10 Jul 2000
Cohesin ensures bipolar attachment of microtubules to sister centromeres and resists their precocious separation

Tomoyuki Tanaka
Jörg Fuchs
Kim Nasmyth
Article 12 Jul 2000
Formation of the male-specific muscle in female Drosophila by ectopic fruitless expression

Kazue Usui-Aoki
Hiroki Ito
Daisuke Yamamoto
Article 13 Jul 2000
Receptor-mediated hydrolysis of plasma membrane messenger PIP₂ leads to K⁺-current desensitization

Evgeny Kobrinsky
Tooraj Mirshahi
Diomedes E. Logothetis
Article 17 Jul 2000
Fringe differentially modulates Jagged1 and Delta1 signalling through Notch1 and Notch2

Carol Hicks
Stuart H. Johnston
Gerry Weinmaster
Article 18 Jul 2000
p95-APP1 links membrane transport to Rac-mediated reorganization of actin

Alessandra Di Cesare
Simona Paris
Ivan de Curtis
Article 18 Jul 2000
The cell-polarity protein Par6 links Par3 and atypical protein kinase C to Cdc42

Gérard Joberty
Clark Petersen
Ian G. Macara

Focus:

Celebrating 25 years of cell biology
Article 17 Jul 2000
A mammalian PAR-3–PAR-6 complex implicated in Cdc42/Rac1 and aPKC signalling and cell polarity

Dan Lin
Amelia S. Edwards
Tony Pawson

Focus:

Celebrating 25 years of cell biology
Article 17 Jul 2000

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Brief Communication

Stimulation of erythropoiesis by inhibiting a new hematopoietic death receptor in transgenic zebrafish

Qiaoming Long
Haigen Huang
Shuo Lin
Brief Communication 19 Jul 2000
BAX-dependent transport of cytochrome c reconstituted in pure liposomes

Mitsuyoshi Saito
Stanley J. Korsmeyer
Paul H. Schlesinger
Brief Communication 19 Jul 2000
Anaphase spindle position is monitored by the BUB2 checkpoint

Andrew Bloecher
Guglielmo M. Venturi
Kelly Tatchell
Brief Communication 19 Jul 2000
The nuclear import function of Smad2 is masked by SARA and unmasked by TGFb-dependent phosphorylation

Lan Xu
Ye-Guang Chen
Joan Massagué
Brief Communication 19 Jul 2000

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Editorial

In search of a function

Editorial 01 Aug 2000

Top of page ⤴

News & Views

Ubiquitin biology: an old dog learns an old trick

Cecile M. Pickart
News & Views 01 Aug 2000
Growth and polarity: the case for Scribble

Sarah Greaves
News & Views 01 Aug 2000
LAP proteins: what’s up with epithelia?

Peter J. Bryant
Adrien Huwe
News & Views 01 Aug 2000
Cell polarity: new PARtners for Cdc42 and Rac

Stuart K. Kim
News & Views 01 Aug 2000
The consequences of incontinentia pigmenti

Sarah Greaves
News & Views 01 Aug 2000
Multi-layered regulation of courtship behaviour

Steven A. Wasserman
News & Views 01 Aug 2000

Top of page ⤴

Book Review

Honest Jim

Robert Weinberg
Book Review 01 Aug 2000
Deciphering the structure of living beings

Paolo Mazzarello
Book Review 01 Aug 2000
Negative thinking: anion channels claim their rights

Michael Pusch
Book Review 01 Aug 2000

Top of page ⤴

Historical Perspective

Lessons from the history of light microscopy

Brad Amos
Historical Perspective 01 Aug 2000

Top of page ⤴

Review Article

Evolution and function of ubiquitin-like protein-conjugation systems

Mark Hochstrasser
Review Article 01 Aug 2000

Top of page ⤴

Volume 2 Issue 8, August 2000

Article

Heat-shock protein 70 inhibits apoptosis by preventing recruitment of procaspase-9 to the Apaf-1 apoptosome

Negative regulation of the Apaf-1 apoptosome by Hsp70

CENP-E forms a link between attachment of spindle microtubules to kinetochores and the mitotic checkpoint

Cohesin ensures bipolar attachment of microtubules to sister centromeres and resists their precocious separation

Formation of the male-specific muscle in female Drosophila by ectopic fruitless expression

Receptor-mediated hydrolysis of plasma membrane messenger PIP₂ leads to K⁺-current desensitization

Fringe differentially modulates Jagged1 and Delta1 signalling through Notch1 and Notch2

p95-APP1 links membrane transport to Rac-mediated reorganization of actin

The cell-polarity protein Par6 links Par3 and atypical protein kinase C to Cdc42

A mammalian PAR-3–PAR-6 complex implicated in Cdc42/Rac1 and aPKC signalling and cell polarity

Brief Communication

Stimulation of erythropoiesis by inhibiting a new hematopoietic death receptor in transgenic zebrafish

BAX-dependent transport of cytochrome c reconstituted in pure liposomes

Anaphase spindle position is monitored by the BUB2 checkpoint

The nuclear import function of Smad2 is masked by SARA and unmasked by TGFb-dependent phosphorylation

Editorial

In search of a function

News & Views

Ubiquitin biology: an old dog learns an old trick

Growth and polarity: the case for Scribble

LAP proteins: what’s up with epithelia?

Cell polarity: new PARtners for Cdc42 and Rac

The consequences of incontinentia pigmenti

Multi-layered regulation of courtship behaviour

Book Review

Honest Jim

Deciphering the structure of living beings

Negative thinking: anion channels claim their rights

Historical Perspective

Lessons from the history of light microscopy

Review Article

Evolution and function of ubiquitin-like protein-conjugation systems

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