Table of contents


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Editorial

Drowning by numbers pE91

doi:10.1038/35014083


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News and Views

bold gamma-tubulin nucleation: template or protofilament? ppE93 - E96

Harold P. Erickson

doi:10.1038/35014084


Convergence of DNA repair and cell-cycle checkpoint control pE95

Angela Eggleston

doi:10.1038/35014087


It's a kar9ochore to capture microtubules ppE96 - E98

Kerry Bloom

doi:10.1038/35014089


Different site, different splice ppE98 - E100

Tom Misteli

doi:10.1038/35014091


Drosophila p53: meeting the Grim Reaper ppE100 - E102

Hermann Steller

doi:10.1038/35014093


COP1 patrols the night beat ppE102 - E104

Raymond J. Deshaies & Elliot Meyerowitz

doi:10.1038/35014095


"Eat me"signals of apoptotic bodies pE104

Valerie Depraetere

doi:10.1038/35014098


Giving protein traffic the green light ppE105 - E106

Linda M. Hendershot

doi:10.1038/35014100


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Review

To be or not to be in the nucleolus ppE107 - E112

Maria Carmo-Fonseca, Luís Mendes-Soares & Isabel Campos

doi:10.1038/35014078


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Articles

Discrete interactions in cell adhesion measured by single-molecule force spectroscopy pp313 - 317

Martin Benoit, Daniela Gabriel, Günther Gerisch & Hermann E. Gaub

doi:10.1038/35014000


Changes in intramitochondrial and cytosolic pH: early events that modulate caspase activation during apoptosis pp318 - 325

Shigemi Matsuyama, Juan Llopis, Quinn L. Deveraux, Roger Y. Tsien & John C. Reed

doi:10.1038/35014006


Dynamic interaction of BiP and ER stress transducers in the unfolded-protein response pp326 - 332

Anne Bertolotti, Yuhong Zhang, Linda M. Hendershot, Heather P. Harding & David Ron

doi:10.1038/35014014


Cargo binding and regulatory sites in the tail of fungal conventional kinesin pp333 - 338

Stephan Seiler, Jochen Kirchner, Christian Horn, Athina Kallipolitou, Günther Woehlke & Manfred Schliwa

doi:10.1038/35014022


Nitric oxide upregulates expression of DNA-PKcs to protect cells from DNA-damaging anti-tumour agents pp339 - 345

Weiming Xu, Lizhi Liu, Graeme C. M. Smith & lan G. Charles

doi:10.1038/35014028


Tollip, a new component of the IL-1RI pathway, links IRAK to the IL-1 receptor pp346 - 351

Kimberly Burns, Jonathan Clatworthy, Laurence Martin, Fabio Martinon, Chris Plumpton, Barbara Maschera, Alan Lewis, Keith Ray, Jürg Tschopp & Filippo Volpe

doi:10.1038/35014038


Immunostructural evidence for the template mechanism of microtubule nucleation pp352 - 357

Thomas J. Keating & Gary G. Borisy

doi:10.1038/35014045

See also: News and Views by Erickson


A new function for the bold gamma -tubulin ring complex as a microtubule minus-end cap pp358 - 364

Christiane Wiese & Yixian Zheng

doi:10.1038/35014051

See also: News and Views by Erickson


Structure of the bold gamma-tubulin ring complex: a template for microtubule nucleation pp365 - 370

Michelle Moritz, Michael B. Braunfeld, Vincent Guénebaut, John Heuser & David A. Agard

doi:10.1038/35014058

See also: News and Views by Erickson


Smooth-muscle contraction without smooth-muscle myosin pp371 - 375

Ingo Morano, Gui-Xuan Chai, Leonidas G. Baltas, Valeria Lamounier-Zepter, Gudrun Lutsch, Monika Kott, Hannelore Haase & Michael Bader

doi:10.1038/35014065


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Brief Communication

Latrunculin alters the actin-monomer subunit interface to prevent polymerization pp376 - 378

Walter M. Morton, Kathryn R. Ayscough & Paul J. McLaughlin

doi:10.1038/35014075


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