1. Hermann Steller is at the Howard Hughes Medical Institute and in the Departments of Biology and of Brain and Cognitive Sciences at the Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, USA. e-mail: hsteller@mit.edu

Abstract

The recent discovery of a Drosophila orthologue of the p53 tumour suppressor promises new insights into the complex function, regulation and evolution of one of the most intensely studied human disease proteins.

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