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Nature Cell Biology 2, E78–E79 (1 May 2000) | doi:10.1038/35010508

A new member of an old family

Andrius Kazlauskas

A newly discovered platelet-derived growth factor (PDGF) isoform, PDGF-CC, is expressed in the mouse kidney during development, at a time and location distinct from those of the other two known PDGFs. These findings, as well as the biochemical characterization of PDGF-CC, indicate that it may represent a new ligand for the PDGF α-receptor.