News and Views abstract
Nature Cell Biology 2, E82 - E83 (2000)
doi:10.1038/35010515
PLC fills a GAP in G-protein-coupled signalling
Craig Montell1
- Craig Montell is in the Departments of Biological Chemistry and Neuroscience, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205-2185, USA
Correspondence to: Craig Montell1 e-mail: cmontell@jhmi.edu
Abstract
An emerging theme in G-protein-coupled signalling is that effectors for
G proteins, such as phospholipase C-
, also function as GTPase-activating
proteins. Such dual roles may contribute to high temporal resolution in G-protein-coupled
signalling cascades.
