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Nature Cell Biology 2, E78 - E79 (2000)
doi:10.1038/35010508

A new member of an old family

Andrius Kazlauskas1

  1. Andrius Kazlauskas is at the Schepens Eye Research Institute, Harvard Medical School, 20 Staniford Street, Boston, Massachusetts 02114, USA.

Correspondence to: Andrius Kazlauskas1 e-mail: kazlausk@vision.eri.harvard.edu


A newly discovered platelet-derived growth factor (PDGF) isoform, PDGF-CC, is expressed in the mouse kidney during development, at a time and location distinct from those of the other two known PDGFs. These findings, as well as the biochemical characterization of PDGF-CC, indicate that it may represent a new ligand for the PDGF alpha-receptor.

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