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Nature Cell Biology 2, E60–E62 (1 April 2000) | doi:10.1038/35008687

Swallowing dynein: a missing link in RNA localization?

Tom Hays & Roger Karess

Localization of bicoid messenger RNA to the anterior cortex of the developing oocyte is essential for correct anterior-posterior patterning of the Drosophila embryo. It now seems that the Swallow protein functions as an adaptor, bridging bicoid mRNA to dynein, a molecular motor that would transport the complex anteriorly along microtubules.