News and Views abstract
Nature Cell Biology 2, E60 - E62 (2000)
doi:10.1038/35008687
Swallowing dynein: a missing link in RNA localization?
- Tom Hays is at the University of Minnesota, Department of Genetics, Cell and Developmental Biology, 6-160 Jackson Hall, 321 Church Street SE, Minneapolis 55455, Minnesota, USA.e-mail: tom-h@biosci.cbs.umn.edu
- Roger Karess is at the CNRS Centre de Génétique Moléculaire, Ave de la Terrasse, 91198 Gif-sur-Yvette, France.
Correspondence to: Roger Karess2 e-mail: Karess@cgm.cnrs-gif.fr
Abstract
Localization of bicoid messenger RNA to the anterior cortex of the developing oocyte is essential for correct anterior-posterior patterning of the Drosophila embryo. It now seems that the Swallow protein functions as an adaptor, bridging bicoid mRNA to dynein, a molecular motor that would transport the complex anteriorly along microtubules.
