1. Brooke McCartney and Mark Peifer are at the University of North Carolina, Chapel Hill, Department of Biology, CB 3280 Coker Hall, Chapel Hill, North Carolina 27599, USA.

Correspondence to: Brooke M. McCartney¹ e-mail: mccartne@email.unc.edu

Abstract

Examination of the tumour suppressor adenomatous polyposis coli (APC) has shown that it may be multifunctional. Recent work has demonstrated dynamic interactions of APC with the microtubule cytoskeleton, supporting the idea that APC has an important function in cell migration.

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