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Nature Cell Biology 2, E48–E50 (1 March 2000) | doi:10.1038/35004078
p53: only ARF the story
Abstract
Two tumour-suppressor proteins — p16INK4A and p19 ARF — encoded by the same genetic locus both have a role in arresting the cell-division cycle. New results have revealed further complexities in the pathways involved.
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