News and Views abstract
Nature Cell Biology 2, E46 - E48 (2000)
doi:10.1038/35004075
Naked antigen-presenting molecules on dendritic cells
Jean Davoust1 & Jacques Banchereau1
- Jean Davoust and Jacques Banchereau are at the Baylor Institute for Immunology Research, 3434 Live Oak, Dallas, Texas 75204, USA.
Correspondence to: Jacques Banchereau1 e-mail: j.banchereau@baylordallas.edu
Abstract
Antigen-presenting cells work to present peptides derived from exogenous and endogenous antigens to circulating T cells, sparking off an immune response. Dendritic cells are unique amongst antigen-presenting cells, not least for their newly described ability to circumvent the need to internalize exogenous antigens before presenting them.
