Moving proteins between cellular locations is proving to be a tightly regulated process, and provides an important mechanism for controlling protein function. The tumour-suppressor protein p53 has been shown to use microtubules to aid nuclear localization, a finding that raises interesting questions about the action of microtubule-disrupting chemotherapeutic drugs.
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Vousden, K., Woude, G. The ins and outs of p53. Nat Cell Biol 2, E178–E180 (2000). https://doi.org/10.1038/35036427
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DOI: https://doi.org/10.1038/35036427
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