Genetically encoded and post-translationally generated variations of tubulin C-terminal tails give rise to extensive heterogeneity of the microtubule cytoskeleton. The generation of different tubulin variants in yeast now demonstrates how single amino-acid differences or post-translational modifications can modulate the behaviour of selected molecular motors.
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Wehenkel, A., Janke, C. Towards elucidating the tubulin code. Nat Cell Biol 16, 303–305 (2014). https://doi.org/10.1038/ncb2938
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DOI: https://doi.org/10.1038/ncb2938
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