During mitosis, kinetochores attach to microtubule plus ends, thus allowing dynamic microtubules to properly segregate chromosomes. How this type of 'end-on' attachment between microtubule plus ends and kinetochores is formed and maintained is unclear. CENP-E, a kinesin-7 family member, is now shown to have a role in associating kinetochores with dynamic microtubule plus ends.
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Gardner, M. CENP-E hangs on at dynamic microtubule ends. Nat Cell Biol 15, 1030–1032 (2013). https://doi.org/10.1038/ncb2836
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DOI: https://doi.org/10.1038/ncb2836
