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Defining an epidermal stem cell epigenetic network

Dynamic changes in the chromatin of adult stem cells are required to establish the gene expression profiles associated with stem cell self-renewal and differentiation. A complex genetic network of chromatin remodellers and epigenetic factors orchestrate these genome-wide changes in human epidermal stem cells.

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Figure 1: Undifferentiated stem cells are maintained by genetic coordination.

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Correspondence to Salvador Aznar Benitah.

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The author declares no competing financial interests.

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Benitah, S. Defining an epidermal stem cell epigenetic network. Nat Cell Biol 14, 652–653 (2012). https://doi.org/10.1038/ncb2538

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