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Nature Cell Biology 11, 680 - 681 (2009)
doi:10.1038/ncb0609-680
Inverted rod nuclei see the light
Christopher Eskiw1 & Peter Fraser1
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Christopher Eskiw and Peter Fraser are at the Laboratory of Chromatin and Gene Expression, The Babraham Institute, Babraham Research Campus, Cambridge, CB22 3AT, UK.
e-mail: peter.fraser@bbsrc.ac.uk;
e-mail: christopher.eskiw@bbsrc.ac.uk
Abstract
Eighty years of microscopy have established a conventional view of nuclear organization: dark-staining heterochromatin at the nuclear periphery and light-staining euchromatin in the interior. This nuclear architecture is inverted in rod cells of nocturnal mammals, demonstrating a unique functional nuclear genome reorganization specifically adapted for light transmission.
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