Eighty years of microscopy have established a conventional view of nuclear organization: dark-staining heterochromatin at the nuclear periphery and light-staining euchromatin in the interior. This nuclear architecture is inverted in rod cells of nocturnal mammals, demonstrating a unique functional nuclear genome reorganization specifically adapted for light transmission.
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Eskiw, C., Fraser, P. Inverted rod nuclei see the light. Nat Cell Biol 11, 680–681 (2009). https://doi.org/10.1038/ncb0609-680
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DOI: https://doi.org/10.1038/ncb0609-680
