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Nature Cell Biology 11, 239–241 (1 March 2009) | doi:10.1038/ncb0309-239

Breast cancer quality control

Cam Patterson & Sarah Ronnebaum

The tumour biology literature is littered with reports on proteins that inhibit tumour progression. In many cases, the corresponding genes are classified as genuine tumour suppressors because their inactivation leads to spontaneous tumour development.