1. Pier Paolo D'Avino is in the Department of Pathology, University of Cambridge, Tennis Court Road, Cambridge CB2 1QP, UK.
2. David M. Glover is in the Cancer Research UK Cell Cycle Genetics Research Group, Department of Genetics, University of Cambridge, Downing Street, Cambridge CB2 3EH, UK.
   e-mail: ppd21@hermes.cam.ac.uk;
   e-mail: dmg25@hermes.cam.ac.uk

Abstract

Cytokinesis ensures proper partitioning of genomic and cytoplasmic material between dividing cells. A key regulator of this process is the centralspindlin complex. Two recent papers report that GAP activity of one of the members of this complex regulates the function of Rho family GTPases during cytokinesis.

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