News and Views
Nature Cell Biology 11, 1279 - 1281 (2009)
doi:10.1038/ncb1109-1279
Tip60-ing the balance in DSB repair
Wolfgang Fischle1
-
Wolfgang Fischle is at the Max Planck Institute for Biophysical Chemistry, Laboratory of Chromatin Biochemistry, D-37077 Gottingen, Germany.
e-mail: wfischl@gwdg.de
Abstract
The tumour suppressor Tip60 is a histone acetyltransferase implicated in transcriptional control and DNA double-strand break repair. Tip60 binds to the heterochromatic histone mark H3K9me3, triggering acetylation and activation of DNA double-strand break repair factors.
MORE ARTICLES LIKE THIS
These links to content published by NPG are automatically generated.
NEWS AND VIEWS
Small molecule versus DNA repair nanomachineNature Chemical Biology News and Views (01 Feb 2008)
Nbs1 moving up in the worldNature Cell Biology News and Views (01 Jul 2005)
See all 5 matches for News And ViewsRESEARCH
Histone H3 methylation links DNA damage detection to activation of the tumour suppressor Tip60Nature Cell Biology Letter (01 Nov 2009)
ATM and Artemis promote homologous recombination of radiation-induced DNA double-strand breaks in G2The EMBO Journal Article (04 Nov 2009)
