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Nature Cell Biology 11, 1277 - 1278 (2009)
doi:10.1038/ncb1109-1277

Spermidine surprise for a long life

Matt Kaeberlein1

  1. Matt Kaeberlein is in the Department of Pathology, University of Washington, Seattle, WA 98195, USA.
    e-mail: kaeber@uw.edu


Identifying therapies to slow down ageing and delay age-associated diseases is a primary goal of ageing-related research. Resveratrol and rapamycin were first found to promote longevity in yeast, and their effects were then extended to several organisms. Spermidine is a new longevity drug that can increase life span in yeast, nematodes and flies, possibly through an effect on chromatin-mediated regulation of gene expression.

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