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Letter

Nature Cell Biology 10, 1106–1113 (1 September 2008) | doi:10.1038/ncb1771

Ripples from neighbouring transcription

Miki Ebisuya , Takuya Yamamoto , May Nakajima & Eisuke Nishida

Transcriptional initiation of each gene is assumed to be independently controlled in mammals. On the other hand, recent large-scale transcriptome analyses have shown that the genome is pervasively transcribed, such that the most of its DNA gives rise to RNAs.